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Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations

    Kazhaleh Mohammadi Sahar Hassannejad Arthur Saniotis Massoud Houshmand

Canadian Journal of Medicine, 2020, Volume 2, Issue 1, Pages 1-6
10.33844/cjm.2020.60491

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Abstract

Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe over time. In this study, we performed a systematic review and meta-analysis of middle east CFTR gene mutations in CF patients to find out the most common mutations in this area. Tree mutations are common in all middle-east populations: Del 508, W1282X and N1303K which can have detection rate as high as 60.9 %.
Keywords:
    Meta-Analysis Cystic fibrosis Randomized clinical trial CFTR F508del N1303K and W1282X
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(2020). Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations. Canadian Journal of Medicine, 2(1), 1-6. doi: 10.33844/cjm.2020.60491
Kazhaleh Mohammadi; Sahar Hassannejad; Arthur Saniotis; Massoud Houshmand. "Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations". Canadian Journal of Medicine, 2, 1, 2020, 1-6. doi: 10.33844/cjm.2020.60491
(2020). 'Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations', Canadian Journal of Medicine, 2(1), pp. 1-6. doi: 10.33844/cjm.2020.60491
Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations. Canadian Journal of Medicine, 2020; 2(1): 1-6. doi: 10.33844/cjm.2020.60491
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