Authors
1
Medical Laboratory Science (MLS) Dep, Knowledge University, Erbil, Kurdistan Region, Iraq
2
Medical Laboratory Science (MLS) Dep, Knowledge University, Erbil, Kurdistan Region, Iraq Department of Anthropology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of science, Poland
3
Medical Laboratory Science (MLS) Dep, Knowledge University, Erbil, Kurdistan Region, Iraq National Institute for Genetic Engineering and Biotechnology, Tehran, Iran
Abstract
Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe over time. In this study, we performed a systematic review and meta-analysis of middle east CFTR gene mutations in CF patients to find out the most common mutations in this area. Tree mutations are common in all middle-east populations: Del 508, W1282X and N1303K which can have detection rate as high as 60.9 %.
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