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Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations

    Authors

    • Kazhaleh Mohammadi 1
    • Sahar Hassannejad 1
    • Arthur Saniotis 2
    • Massoud Houshmand 3

    1 Medical Laboratory Science (MLS) Dep, Knowledge University, Erbil, Kurdistan Region, Iraq

    2 Medical Laboratory Science (MLS) Dep, Knowledge University, Erbil, Kurdistan Region, Iraq Department of Anthropology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of science, Poland

    3 Medical Laboratory Science (MLS) Dep, Knowledge University, Erbil, Kurdistan Region, Iraq National Institute for Genetic Engineering and Biotechnology, Tehran, Iran

,
10.33844/cjm.2020.60491
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Abstract

Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe over time. In this study, we performed a systematic review and meta-analysis of middle east CFTR gene mutations in CF patients to find out the most common mutations in this area. Tree mutations are common in all middle-east populations: Del 508, W1282X and N1303K which can have detection rate as high as 60.9 %.

Keywords

  • Meta-Analysis
  • Cystic fibrosis
  • Randomized clinical trial
  • CFTR F508del
  • N1303K and W1282X
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Canadian Journal of Medicine
Volume 2, Issue 1
August 2020
Page 1-6
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  • PDF 333.52 K
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  • Article View: 998
  • PDF Download: 758

APA

Mohammadi, K. , Hassannejad, S. , Saniotis, A. and Houshmand, M. (2020). Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations. Canadian Journal of Medicine, 2(1), 1-6. doi: 10.33844/cjm.2020.60491

MLA

Mohammadi, K. , , Hassannejad, S. , , Saniotis, A. , and Houshmand, M. . "Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations", Canadian Journal of Medicine, 2, 1, 2020, 1-6. doi: 10.33844/cjm.2020.60491

HARVARD

Mohammadi, K., Hassannejad, S., Saniotis, A., Houshmand, M. (2020). 'Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations', Canadian Journal of Medicine, 2(1), pp. 1-6. doi: 10.33844/cjm.2020.60491

CHICAGO

K. Mohammadi , S. Hassannejad , A. Saniotis and M. Houshmand, "Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations," Canadian Journal of Medicine, 2 1 (2020): 1-6, doi: 10.33844/cjm.2020.60491

VANCOUVER

Mohammadi, K., Hassannejad, S., Saniotis, A., Houshmand, M. Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations. Canadian Journal of Medicine, 2020; 2(1): 1-6. doi: 10.33844/cjm.2020.60491

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